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Eliminating the Renal dysplasia (Cox-2) mutant alleles from breeding populations
– why breeders must act now for the future health of canines.
A heath survey published in 2014 by The Kennel Club (UK) lists kidney failure as the 4th leading cause of death among 5,663 dogs from 179 breeds. The age of onset from this survey was 7-13 years of age. The proportion of dogs that died from kidney failure in this survey was 4.22%." This data is consistent with our findings that 3-5% of adult dogs with one or two copies of a RD mutant allele will die from kidney failure. So many breeds that have a high frequency of the RD alleles suggesting that RD is probably the most frequent cause of renal failure in dogs. As long as these alleles remain in breeding population the lives of countless dogs will be needlessly shortened.
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HOW A MUTATION FOR COAT COLOR IN MICE
HELPS US UNDERSTAND RENAL DYSPLASIA
| Click here to view article | Summary of article |
